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02/19/13
Trends in Technical Careers. 4. Bridging the gap between academic research and practical outcomes R&D
Filed under: Observ. Trends, Alternate Career Paths
Posted by: site admin @ 4:13 pm

At a technical meeting recently, I attended a
Special Interest Group forum on the Barriers
to Academic Drug Discovery– cultures, constraints
and motivations.  Discussions like this define academic
and industrial government working space and tactics.

Whereas as
Pharma-industry and            academia prefers
government seek

quick kills‘,                               longer term horizons,
                                                    exploring in depth
portfolios,                                 research for the next
                                                    grant [initial results showing
                                                    potential]
timelines &,                               personal discovery and
competences                               reputation

efficient innovation,                   intellectual leaps.
                                       
Striking stories where unexpected, quantum leap
discoveries in academic labs have led to incredible
commercial leaps. like Thomas Brock and Hudson
Freeze’s 1969 discovery of Thermus aqauticus Taq,
a bacterium in the hotsprings of Yellowstone.  Its DNA
polymerase has uniquely evolved to survive Yellowstone’s
hot springs.  This enzyme is the prototype for Kary
Mullis’s polymerase chain reaction that has transformed
modern life from legal systems to advanced therapies
for diseases.

Discussion covered journal publication, but too often
      contains unrealiable data, only successes get into
      print, when failures might be even more valuable.
Reliable databases with common easy to manipulate
     formats was another forum topic.

 

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